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Syllabus

Posted by Terese Wignot, 9/2/02 at 2:49:01 PM. Chemistry 361
Biochemistry:Structure and Function
Terese M. Wignot,PhD
267 Stark Learning Center
Department of Chemistry
(570)408-4627
wignot@wilkes.edu
Office Hours: see Weekly Schedule

SYLLABUS Required Text: "Principles of Biochemistry" by Lehninger, Nelson and Cox, 5^th edition. Worth Publishers, 2008. ISBN-13:978-0-7167-7108-1

Major Objectives:Students in all chemistry courses are expected:
A1. To demonstrate proficiency in analysis, organization, interpretation, and presentation of chemical data.
A2. To express chemical concepts with quantitative relationships and to interpret the results obtained from the use of these quantitative relationships in terms of the chemical concepts conveyed in this format.
A3. To use written communication in a cogent and coherent form that demonstrates understanding of chemical concepts.
A4. To develop critical thinking and problem-solving skills in synthesizing information.
A5. To appreciate the relevance of chemistry to everyday life.
A6. To recognize that the various areas of chemistry are interrelated and require integration of basic chemical principles, including chemical formulae and nomenclature, chemical reactions and stoichiometry, chemical equilibria and acid-base theory, and molecular structure.

Course Objective: Students in this courses are expected:
B1. To demonstrate an understanding of basic chemical principles including solution chemistry, acid/base chemistry, and intermolecular forces.
B2. To demonstrate an understanding of the structure, properties and function of proteins, specifically, myoglobin and hemoglobin.
B3. To demonstrate an understanding of the structure and function of enzymes, reaction and enzyme kinetics.
B4. To demonstrate proficiency in analysis, organization, interpretation, and presentation of enzyme kinetic data.
B5. To demonstrate an understanding of the structure and function of nucleic acids; replication, transcription, and translation.
B6. To demonstrate an understanding of the structure and function of lipids; membrane composition and function.

Grading: Suggested homework problems from each chapter of the text are given in the course outline. Additional homework will be assigned and graded. Three exams will be given as well as a cumulative final exam. Homework, tests and the final will based on lecture material and homework problems. All exams are mandatory and no make-up exams will be given. In case of illness, as demonstrated by a medical certificate and upon approval of the Dean, special arrangements will be made.

Tentative Dates* Tentative %*

Homework Due 5

Wed Sept 30 Exam 1 Fri Oct 2 20-25**

Wed ONov 4 Exam 2 Fri Nov 6 20-25**

Mon Dec 7 Exam 3 Wed Dec 9 20-25**

Final Set by Registrar 30

*- the %s and dates are subject to change as the semester progresses at the discretion of the instructor.
**- the highest exam score will count for 25% of your overall grade and the other two exams will count for 20% toward your overall grade.
Attendance is required under University policy. The withdraw policy of the University will be strictly enforced.

Percentage Grade

>90 4.0

85-89 3.5

80-84 3.0

75-79 2.5

70-74 2.0

65-69 1.5

60-64 1.0

<60 0

All tentative dates, point distributions and cut offs are subject to change at the discretion of the instructor.

Withdraw Policy: See pages 59-60 of the Wilkes University Student Handbook. Student Handbook

The University policy will be strictly enforced.

Course Outline
Click on the highlighted topic to download Powerpoint Presentaions

TOPIC	TEXT CHAPTER	PROBLEMS
Micro/Macro Structure Cells	1	6,7,11,13
Water & Buffers Properties_water	2	1,5,7,12,13,15,17,27,30
Amino Acids, Peptides & Proteins AminoAcids	3	2,3,5,10,11,13,14,15,18
3-D Structure of Proteins Structure_protein,Protein Purification,Protein Sequencing	4,3	1,4,6
Protein Function Mb_O2Binding,Hb_O2Binding	5 (Mb&Hb only)	3,5,6,7
Enzymes Enzymes	6 exclude regulatory enzymes	1,3,4,7,8,11,12,15,17,18,19
DNA & RNA DNA Structure,DNA_rep,DNA Sequencing,RNA,Translation	8 additional sections in 25-27	Ch.8:1,2,11,12, Ch.25:1,2,4,5,9, Ch.26:2,6, Ch.27:1,2,4,5,9,12
Lipids Lipids&membranes	10	2,3,7,9,11,18
Membranes & Transport	11	3,4,6,8,13,15,19

EXTRA CREDIT: EXTRA CREDIT: Extra credit will be assigned on a first come first serve basis for topics and dates. The projects will involve filling the display cases on the second floor by SLC 201, SLC 275 and SLC 261. The projects will be displayed until another project replaces it. It is the students¢â¡Á responsibility to put up the display on the due date. The topic must come from a current scientific magazine or journal corresponding to a lecture topic and must be approved by the instructor. The project must include at least four full pages of written text and three illustrations to fill the case. Appearance is important. The text can be distributed among the illustrations. Four references must be cited. No internet references are allowed. Each Monday of the semester is available starting the week of September 7 through Monday December 7 and there are three display cases available per week. You must sign up for a date by October 8. Students can work in pairs and each student can receive 0 to 3 points added to their overall grade.

Last update: Friday, August 28, 2009 at 1:44:20 PM.

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