Chemistry 362
Biochemistry:Metabolsim
Terese M. Wignot,PhD
267 Stark Learning Center
Department of Chemistry
(570)408-4627
wignot@wilkes.edu
Office Hours: see Weekly Schedule
SYLLABUS
Course Information
Class Hour: Monday,Wednesday, Friday 12:00-12:50PM
Location: SLC 270Text
"Lehningher
Principles of Biochemistry" by Nelson & Cox , 4rd edition ISBN
0-7167-4339-6.
Available in the bookstore.
http://guweb2.gonzaga.edu/faculty/cronk/biochem/images/Q-cycle-animation.gif
Major Objectives
Students in all chemistry courses are expected:
A1. To demonstrate proficiency in analysis, organization,
interpretation,
and presentation of chemical data.
A2. To express chemical concepts with quantitative relationships and
to interpret the results obtained from the use of these
quantitative relationships in
terms of the chemical concepts conveyed in this format.
A3. To use written communication in a cogent and coherent form that
demonstrates understanding of chemical concepts.
A4. To develop critical thinking and problem-solving skills in
synthesizing information.
A5. To appreciate the relevance of chemistry to everyday life.
A6. To recognize that the various areas of chemistry are interrelated
and require integration of basic chemical principles,
including chemical formulae
and nomenclature, chemical reactions and stoichiometry, chemical
equilibria
and acid-base theory, and
molecular
structure.
Course Objectives
Students in this course iare expected:
B1. To understand the structure and metobolic function of
carbohydrates.
B2. To understand the catabolism and anabolism of carbohydrates
including molecular transformation of biomolecules, the regulation of
the
pathways and bioenergetics.
B3. To understand the catabolism and anabolism of fats including
molecular transformation of biomolecules, the regulation of the
pathways
and bioenergetics.
B4. To understand the catabolism and anabolism of amino acids
including molecular transformation of biomolecules, the regulation of
the
pathways and bioenergetics.
B5. To understand oxidative phosphorylation.
B6. To understand the interaltionship between catabolic pathways.
B7. To understand the reciprocal regulation of catabolic and anabolic
pathways.
Grading
Homework problems will be assigned with each chapter from the text as
well
as additional homework problems which will be handed in or submitted
on-line
and graded. Three hour exams will be given and as well as a cumulative
final exam. All exams are mandatory and no make-up exams will be given.
In case of illness, as demonstrated by a medical certificate and upon
approval
of the Dean, special arrangements will be made.
Plagiarism/Cheating. The Wilkes University community shares "a deep commitment to academic honest and integrity". Penalties for violation of the University plagiarism policy range from a zero on the assignment or test to course failure. Sufficiently egregious cases of plagiarism may be referred to the Student Affairs Cabinet for further disciplinary sanctions. The University recognizes the following as violations of Intellectual Responsibility,plagiarism, cheating and collusion. Furthermore the University also recognizes various forms of plagiarism, deliberate, unintentional and self. Additional details can be found in the Student Handbook, p. 54-55.
| Test |
Percentage
|
| Homework |
5 |
| Exam 1 |
20 or 25* |
| Exam 2 |
20 or 25* |
| Exam 3 |
20 or 25* |
| Final |
30 |
| Total |
100 |
*- your highest exam scoe will be worth 25% the other two exams are worth 20%
EXTRA CREDIT
Extra credit will be assigned on a first come first serve basis for
topics and dates. The projects will involve filling the display cases
on
the second floor by SLC 201 and SLC 275 . The projects will be
displayed
for a week. It will be the students responsibility to put up the
display
on Monday. Topics should be chosen from a current scientific magazine
or
journal. The project must include at least four pages of written text
and
three illustrations to fill the case. Appearance does count. The text
can
distributed among the illustrations. Two references, other than your
book,
must be used and cited. No web references allowed. Each Monday of the semester is available
starting
January 19 through Monday April 27 and there are four display cases
available
per week. You can sign up for a date and topic before February 27. Zero to
three points will be added to the overall grade for extra credit.
Percentage
|
Grade |
| >90 |
4 |
| 85-89 |
3.5 |
| 80-84 |
3 |
| 75-79 |
2.5 |
| 70-74 |
2 |
| 65-69 |
1.5 |
| 60-64 |
1 |
| <60 |
0 |
The course outline below contains the topics to be covered and the order the topics will be covered. Dates may b adjusted at the discretion of the instructor.
Chemistry 362
Class Schedule
Spring 2007 |
| Week |
Chapter |
Lecture Topic |
Problems Text |
| Jan 12 |
7, Part III |
Overview of
Metabolism/Carbohydrates CHO (exclude
glycoconjugates) |
7:9,16,17 |
| Jan 19 |
13 |
Bioenergetics (Exclude redox)
Bioenergetics_ATP |
13: 2,3,4,6,8,9 a-d,11,16 |
| Jan 26 |
14 |
Vitamins as Cofactors coenzymes_vitamins,
Glycolysis |
14:3,5,6,7,9,11,14,16,17,21,22 |
| Feb 2 |
14 cont. |
Glycolysis |
14: see above |
| Feb 9 |
HW1_2/11
15
|
Exam 1_2/13
Pentose Phosphate/Glycogen
|
Ch.713,14
|
| Feb 16 |
15 |
Glycogen Anabolism only glycogen_metabolism |
15:3,4,7,8,9,11 |
| Feb 23 |
16 |
Citric Acid Cycle (exclude
glyoxylate) |
16:4,6 a,b,8,10,11,16,19,20 |
| Mar 2 |
Spring |
Break ENJOY!! and & |
Catch UP |
| Mar 9 |
16,17 |
Citric Acid cont.
Fatty Acid
OxidationLipid_Catabolism |
17:3,5,6,11,13,14,17 |
| Mar 16 |
HW 2_3/18
|
Exam 2 3/20
|
Chs. 15,16,17 |
| Mar 23 |
13 |
Bioenergetic (redox) |
13:18,19,21,22 |
| Mar 30 |
19 |
Oxidation Phosphorylation ETC_ATPase |
19:1,3,4,6,7,8,10,12,17,18 |
| Apr 6 |
18 |
Easter Break
Amino Acid Oxidation
urea&aa_metabolism |
18:1,4,6,7,11 |
| Apr 13 |
21 and 22 |
Lipid
Bioynthesis
FattyAcids Synthesis
Nucleotide Synthesis
Nucleotide_synthesis |
21:1,4,5,6,9,10 |
| Apr 20 |
HW3_4/22
|
Exam 3_4/24 |
Ch. 1318,19,21 |
| Apr 27 |
|
review |
classes end 4/29
|
| May |
1 |
FINAL EXAMS BEGIN |
Good Luck |
|
|
|
